Rare Book Monthly

Articles - February - 2023 Issue

Google is Using Old Books and New Technology to Combat Disease

A recent story on the Google Research blog quickly caught my eye: Using new technology and old books to combat disease. We tend to think of old books as a source of information about the past, which they certainly are, but the headline indicated the people at Google Brain were using them to solve today's major problems.

 

The issue they were tackling concerned insect-borne diseases. Mosquitoes and ticks spread dangerous diseases such as malaria and lyme disease. Add to that how annoying the itching bites can be and there is good reason to seek new ways to repel these pests. The most common repellent for mosquitoes, the active ingredient in many of the repellents you find in the store, is Deet (technically, N,N-diethyl-meta-toluamide). It was discovered 80 years ago after extensive government research. However, it does have certain drawbacks, such as damaging some types of fabrics, not working with all pests, and possibly some negative effects on people.

 

What the Google researchers discovered was the government had carried on extensive testing in the 1940s when they selected Deet, but what they tested and what were the results was virtually impossible to find. It was stashed away in various places with no practical way to locate it all. However, these were Google researchers and they were aware that Google had scanned and preserved reams of this old stuff as part of Google Books. This allowed them to locate these old reports and review them. What they found was surprising. The government had tested thousands of potential repellents.

 

Exactly how Google Brain used all this data is beyond the scope of this article, which is another way of saying the computer functions and science are beyond my understanding. The computers are using AI (Artificial Intelligence) to do comparisons of promising molecules to find others that may be useful. Eventually, they came up with a list of 10 molecules that may be more effective than Deet. Further testing will be needed. Hopefully, they will find better repellents that will save lives in areas plagued by disease-bearing insects while making our picnics more pleasant.

 

The issue for us is old books, and the application of new technology to them. Google Books now has 40 million volumes scanned into their database. This is definitely the information age and that is a lot of data. The issue now is making connections, using the existing data to learn things no one realized was there, and applying it to questions we want to answer today. That is where AI comes in. It can “think” at computer speed, not human speed, and it can sort through voluminous amounts of data in split seconds. Perhaps you've had a chance to ask questions of, or even get stories or poems written on demand for you by ChatGPT. Maybe you have created some unique images through Stable Diffusion. What they can do with AI and data is astonishing, at least to those of us who grew up in the age of pencils and paper. They are fun to play around with, but as Google Brain is proving, AI is serious business. Combine it with data from old books and other sources, and there is no telling what you may discover.

 

In our own case, over the past 20 years we have put together a database of over 12.5 million records from auctions and other sources pertaining to sales of old books. It has enabled us to not only find descriptions and prices from the past, but to create a scale for estimating the current value of old prices based on an index generated strictly from book sales. We recently developed a method of using the database to estimate the value of entire collections, not just one book at a time. We can estimate how frequently a particular title is likely to come up at auction in the future. We can determine how frequently certain words are used in descriptions of a particular title. Still, there is much more to be learned, not only about books but about the interests of people at various times, and which changes predict our interests in the future. As long as the data has been accumulated, AI will enable us to learn much more than we ever dreamed possible. These are exciting times.

Rare Book Monthly

  • Forum Auctions
    Fine Books, Manuscripts and Works on Paper
    28th May 2026
    Forum, May 28: Book of Hours.- Heures de nostre dame a l'usaige de Romme, Paris, Antoine Chappiel pour Germain Hardouin, [1504]. £6,000-8,000
    Forum, May 28: Colonna (Francesco). La Hypnerotomachia di Poliphilo, second edition, Venice, Sons of Aldus Manutius, 1545. £15,000-20,000
    Forum, May 28: The Christ Child holding a crystal orb and surrounded by banderoles with devotional exhortations, on a leaf most probably from a Book of Hours, [Southern Netherlands, last decades of the fifteenth century]. £2,000-3,000
    Forum Auctions
    Fine Books, Manuscripts and Works on Paper
    28th May 2026
    Forum, May 28: Jackson (Shirley). The Haunting of Hill House, first English edition, signed presentation inscription from the author to Claude Fredericks, 1960. £2,000-3,000
    Forum, May 28: Lennon (John). In His Own Write, first edition, first impression, signed by the author, 1964. £3,000-4,000
    Forum, May 28: Doves Press.- Keats (John). [Poems], one of 200 copies on paper, Doves Press, 1914. £5,000-7,000
    Forum Auctions
    Fine Books, Manuscripts and Works on Paper
    28th May 2026
    Forum, May 28: Rodrigues (João Barbosa). Sertum Palmarum Brasiliensium, 2 vol., first and only edition, Brussels, 1903. £8,000-12,000
    Forum, May 28: Newton (Sir Isaac). Philosophiae naturalis principia mathematica…editio ultima, auctior et emendatior, Amsterdam, Sumptibus Societatis, 1714. £8,000-12,000
    Forum, May 28: Kepler (Johannes). Ad Vitellionem paralipomena, wuibus astronomiae pars optica traditur, first edition, Frankfurt am Main, 1604. £5,000-7,000
    Forum Auctions
    Fine Books, Manuscripts and Works on Paper
    28th May 2026
    Forum, May 28: Tagliacozzi (Gaspare). De Curtorum Chirurgia per insitionem, libri duo, first edition, Venice, Gasparo Bindoni, 1597. £7,000-10,000
    Forum, May 28: Lootsman (Jacobsz). The Lightning Colomne, or Sea-Mirrour, containing the Sea-Coasts of the Northern, Eastern and Western Navigation..., 1670. £8,000-12,000
    Forum, May 28: Ribelles y Helip (José), Attributed to. An album comprising 33 finely executed watercolours of Spanish costume, bull-fighting scenes, and other genre subjects, [circa 1830]. £10,000-15,000

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